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Competitiveness binding experiments carried out in CHO mobile membranes transfected with human CB1 or CB2 receptors disclosed affinity values during the small nanomolar vary for equally the analyzed compounds AM-2201 and MAM-2201 (Desk 1). Equivalent benefits were being obtained assessing affinity values of The 2 synthetic cannabinoids in mouse tis

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The process was executed bilaterally (Total score: 6). Pinna reflex was assessed by touching pavilions (still left and suitable) with a skinny hypodermic needle: very first the inside pavilions then the external. This test was recurring twice for either side providing a rating of 1 if a reflex was current and 0 if it wasn't present (General rating:

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